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ITGB1 anticorps

L’anticorps Souris Monoclonal anti-ITGB1 a été validé pour ELISA et Coat. Il convient pour détecter ITGB1 dans des échantillons de Humain.
N° du produit ABIN6937596

Aperçu rapide pour ITGB1 anticorps (ABIN6937596)

Antigène

Voir toutes ITGB1 Anticorps
ITGB1 (Integrin beta 1 (ITGB1))

Reactivité

  • 229
  • 114
  • 98
  • 21
  • 19
  • 19
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  • 10
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  • 3
  • 2
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  • 2
  • 2
  • 1
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  • 1
  • 1
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  • 1
Humain

Hôte

  • 155
  • 87
  • 24
  • 12
  • 8
  • 1
Souris

Clonalité

  • 143
  • 140
  • 1
Monoclonal

Conjugué

  • 128
  • 25
  • 23
  • 15
  • 10
  • 8
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  • 4
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Cet anticorp ITGB1 est non-conjugé

Application

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ELISA, Coating (Coat)

Clone

12G10
  • Specificité

    Recognizes CD29. Binds to the cell membrane of T- and B- lymphocytes, monocytes, platelets, fibroblasts, endothelial cells, mast cells and smooth muscle cells. CD29 is an adhesion receptor and co-stimulatory molecule. This antigen was initially characterized as GPIIa on platelets and as the common b1 subunit of the very late antigen (VLA) protein family. CD29 forms a non-covalent heterodimeric complex with integrin alpha subunits. It also mediates adhesion to invasion and thrombospondin.

    Aucune reactivité croisée

    Souris, Rat (Rattus)

    Réactivité croisée (Details)

    Human. Does not react with Mouse or Rat.

    Purification

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogène

    Purified human beta 1 integrin from HT1080 fibrosarcoma cell extract.

    Isotype

    IgG1 kappa
  • Indications d'application

    Known_Application: ELISA (For coating use Ab at 1-5 μg/mL, order Ab without BSA) Optimal dilution for a specific application should be determined.

    Positive_Control: HT1080 whole cell lysate. HeLa cell line.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Agent conservateur

    Azide free

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Date de péremption

    24 months
  • Antigène

    ITGB1 (Integrin beta 1 (ITGB1))

    Autre désignation

    ITGB1

    Sujet

    Fibrinogen Receptor beta subunit, FNRB, Glycoprotein IIa (GPIIA), Integrin beta-1 (ITGB1), integrin VLA-4 beta subunit, MDF2, MSK12, Very Late Activation Protein beta Polypeptide, VLA-4 subunit beta, VLA-BETA, VLAB,CD29 (Stem Cell Marker)
    Cellular localisation: Cell Surface

    Poids moléculaire

    110kDa (non-reduced) & 130kDa (reduced)

    ID gène

    3688, 643813

    UniProt

    P05556

    Pathways

    Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome
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